Travel Vaccinations for Central African Republic

Rift Valley fever (RVF) is an acute, fever-causing viral disease that usually affects domesticated animals (such as cattle and sheep), but can also infect and cause illness in humans. The majority of human infections are caused by direct or indirect contact with the blood or organs of infected animals.

Crimean-Congo haemorrhagic fever (CCHF) is primarily spread to humans either by infected ticks or animal blood. Human-to-human transmission can also occur resulting from close contact with the blood, organs or other bodily fluids of an infected person.

West Nile virus (WNV) is spread by mosquitoes in many countries. There are usually no symptoms, although some people develop mild flu-like symptoms, nausea and skin rash. The virus is not contagious and should get better without any treatment.

Zika virus is usually transmitted by the bite of an infected Aedes species mosquito. These mosquitoes are most active during the day, especially during mid-morning, then late afternoon and dusk through to evening. For most people it's a very mild infection with minor or no symptoms, but is more of a risk to pregnant woman as it could result in certain birth defects.

Bacterial infection from bite from infected ticks. Most common between April-November and in rural, camping and hiking areas. Causes redness around site of bite and symptoms usually within 2 weeks, such as fever, muscle pain, headache and rash.

Chikungunya is a viral disease transmitted to humans by infected mosquitoes and it causes fever and severe joint pain. Other symptoms include muscle pain, headache, nausea, fatigue and rash. Joint pain is often debilitating and can vary in duration. The disease shares some clinical signs with Dengue, and can be misdiagnosed in areas where Dengue is common. There is no cure for the disease. Treatment is focused on relieving the symptoms.

A parasitic disease transmitted by the bite of an infected sandfly. Cutaneous Leishmaniasis (the most common): Causes skin lesions, mainly ulcers on exposed parts of the body, causing scars and serious disability. 90% of cases are in the Americas, the Mediterranean basin, the Middle East and Asia. Visceral Leishmaniasis (the most dangerous): Causes enlarged spleen and liver, anaemia, weight loss and irregular bouts of fever. Highly endemic in the Indian Subcontinent and East Africa. Mucotaneous (the least common): Causes partial or total destruction of the mucous membranes in the nose, mouth and throat. Most cases are found in Peru, Bolivia and Brazil.

Schistosomiasis, also called bilharzia, is an infection caused by a parasitic worm that lives in fresh water in subtropical and tropical regions. Avoid swimming in fresh water rivers, streams and lakes if you can. You often don't have any symptoms at first, but after a few weeks may develop a rash, high temperature, cough, diarrhoea and joint pain. Schistosomiasis can usually be treated successfully with a short course of a medication that kills the worms.

Human African trypanosomiasis, also known as sleeping sickness, is a parasitic disease transmitted to humans by the bite of an infected tsetse fly, which is only found in rural Africa. Initial symptoms include severe headache, insomnia, enlarged lymph nodes, anaemia and rash.